If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...
Once failed in high school chemistry due to a teacher’s judgement, Tomas Lindahl later reshaped the same discipline. Awarded the 2015 Nobel Prize in Chemistry for his pioneering DNA repair research, ...
Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...
DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among the most dangerous forms of DNA damage and immediately trigger the cell's ...
DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...
Unrepaired DNA-protein crosslinks (DPCs) – highly toxic tangles of protein and DNA – cause a process that leads to premature ...
DNA can be damaged by normal cellular processes as well as external factors such as UV radiation and chemicals. Such damage can lead to breaks in the DNA strand. If DNA damage is not properly repaired ...
A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...
If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...
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